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Plasma citrulline is a biomarker of enterocyte mass and an indicator of parenteral nutrition in HIV-infected patients

Both are preclinical and investigational, not approved for human or veterinary use

Higher doses produce increased incidence and severity of gastrointestinal symptoms, which explains why clinical protocols use gradual dose escalation starting at 0.25 mg weekly and incrementally increasing every 4 weeks

Huang X, Zhang Y, Jiang Y, Li T, Yang S, Wang Y et al (2024) Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration

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