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This work was supported by the Swedish Research Council Postdoc FellowshipC0657401 (to LJ), Stanford University Medical Scholars Research Program, Howard Hughes Medical Institute Medical Fellows Program (to GSK) and NIH/NIDCD K08DC011043, RO1DC01910, Department of Defense W81XWH-14-1-0517, Akiko Yamazaki and Jerry Yang Faculty Scholar Fund, and California Initiative in Regenerative MedicineRN3-06529 (to AGC)

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In another study, six weeks of 1000 mg NR supplementation per day for CKD patients improved mitochondrial metabolism, yet no effects were observed in the physical endurance of skeletal muscle 315