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If any of these occur, it's advisable to discard the vial and prepare a new sample to ensure research integrity.

Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness

Both types of cases, clinical HT-1 ( FAH mutation) without circulating SA, and persistent SA due to maleylacetoacetic isomerase deficiency (mutation in GSTZ1 , not FAH ) without HT-1-like clinical symptoms, have recently been described

Declines with age (50% reduction by age 60)

doi: 10.3389/fmicb.2025.1526250 Received 11 November 2024 Accepted 13 January 2025 Published 03 February 2025 Volume 16 - 2025 Edited by Sebastian Guenther, University of Greifswald, Germany Reviewed by Eugene A