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[DOI] [PubMed] [Google Scholar] 54.Singh R.B., Niaz M.A., Kumar A., Sindberg C.D., Moesgaard S., Littarru G.P

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Last updated: March 22, 2026 Introduction to Inflammatory Bowel Disease The etiology of Inflammatory bowel disease (ulcerative colitis and Crohns disease) is complex, with genetic predisposition, an altered microbiome, environmental factors and a weakened epithelial (gut) barrier function triggering a chronic immune response in the mucosal layer