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Replicability was confirmed across individual mice and cell cultures, with data points included if they met technical validity standards (e.g., perfusion, tissue preparation, staining, recordings, imaging)

Because weight loss and alterations in body image can be distressing for patients and their caregivers, appropriate psychosocial support should be provided

Oral Safety, Side Effects, and Who Should Be Cautious For most healthy adults, L-carnitine is generally well tolerated, especially at typical supplemental doses