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Although the number of patent litigation cases in Germany has declined due to the growing use of the UPC, the German courts remain highly regarded for their cost-efficient and reliable IP enforcement, supported by specialized chambers and a strong tradition of granting injunctive relief

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The gene localized to chromosome 22q13qter, and a number of mutations have been identified

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Thus, the pro-fibrotic ingredients such as TGF1, oxidative stress, and ROCK are indicative of penile fibrotic process, and inhibiting these factors by anti-fibrotic agents such as iNOS, NO, and cGMP could ameliorate or block this process