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doi: 10.1006/gcen.2001.7619 146 MarchettiCObertGDeffosezAFormstecherPMarchettiP

In turn, LATS1/2 phosphorylation triggers YAP activation, causing YAP capture by 4-3-3 proteins in the cytosol or degradation by SCF-TRCP E3 ubiquitin ligase-mediated ubiquitin-proteasome signaling