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In EMPA-KIDNEY, which enrolled more than 6,600 patients, Jardiance combined with standard of care elicited a 28% relative risk reduction in kidney disease progression, defined as end-stage kidney disease, or cardiovascular death compared with placebo plus standard of care

ROS are highly reactive substances concentration of which depends on the physiological state of the organism

LLPS is associated with the formation of a water-rich phase containing water and hydrophilic species in the bulk, which can lead to an increase of water uptake for the particle of given diameter 24,25