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Nebulized treatment provides patients with COPD an alternative administration route that avoids the need for inspiratory flow, manual dexterity, or complex hand-breath coordination

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5c), which could be attributed to the thus-generated ROS from ILD, as verified already in Supplementary Fig

Ferroptosis intersects with these inflammatory pathways under conditions of sustained oxidative stress and iron dysregulation, further exacerbating epithelial damage during advanced stages of disease

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In addition, miR-155 can disrupt the balance between Treg and Th17 cells by interfering with Foxp3 expression and thus weakening Treg function [48]