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Consequently, the expression of mitochondrial uncoupling protein 2 and the AMP-to-ATP ratio were increased, thereby stimulating the oxidative metabolism in the liver and adipose tissue (88, 91)

The quaternary N-methylated quinoline ring with a 5-amino group enables selective recognition by the NNMT active site, where it acts as a competitive inhibitor

8 Toxicity and side effects The toxicological problems associated with herbal medicines are a major public health issue

Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease

The study protocol was approved by the ethics committee of Louisiana State Health Sciences Center-Animal Care Committee (Animal Care protocol number P-15-006), and all the methods were carried out following the approved guidelines

doi:10.3949/ccjm.87a.19072 16