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119 Additional studies have shown that aggregated mutant SOD1 has low Cu content both in cultured cells and in the spinal cord of transgenic SOD1 mice, regardless of the mutant proteins ability to bind Cu 120,121

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Imbalances in histone acetylation modifications lead to the development of various tumors

Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism

PMID 22467107

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