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LCN2, an acute phase protein secreted by activated astrocytes or neutrophils, has been shown to promote neuronal ferroptosis via downregulation of SLC7A11 in various CNS disease models, including epilepsy and diabetes-associated ischemic stroke (Zhou Z

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The main focus of the intervention was that BPC 157 rapidly activates collaterals due to its particular direct and rapid effect on vessel presentation, the bypassing of one or more of the vascular obstructions and thereby achieving a therapeutic effect

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Another possibility is that because this study was performed at a dementia clinic, the doctor and health care providers provided other forms of care to stimulate brain function, including better daily living, such as a regular lifestyle, regular meals, reading newspapers and participating in social activities, which may have influenced the improvement in the MMSE score

doi: 10.1002/0470090839.ch15 59 BatesKHerzogED