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Dyla et al (19) demonstrated the key role of P-type Wilson ATPase in preventing copper deficiency or toxicity by facilitating the transfer of copper from the liver to the secretory pathway

The monomeric G proteins have the same GTP-binding and GTPase properties as G subunits of heterotrimeric G proteins (Figure 2), and they both use the bound GTP to time their active signaling life time

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Cell lines Human endothelial cells HUVEC (CC-Y1285) were purchased from EK-Bioscience (Shanghai, China)

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Specificity protein 1 (sp1) oscillation is involved in copper homeostasis maintenance by regulating human high-affinity copper transporter 1 expression