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Parasympathetic and Sympathetic dysfunction and ME/CFS are apparently joined at the hip. Ehlers-Danlos Syndrome (EDS) and Hypermobile patients may have a genetic predisposition to autoimmunity and mitochondrial dysfunction

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All arterial catheters were flushed daily with heparin solution (50 units heparin in phosphate-buffered saline at 0.1 M, pH 7.4)