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Symptoms of vitamin B12 deficiency include (1): chronic fatigue shortness of breath heart palpitations tingling or numbness in the extremities poor balance loss of concentration poor memory disorientation mood changes incontinence insomnia People most at risk of developing a deficiency include older adults, as well as those who smoke, abuse alcohol, or follow a vegetarian or vegan diet

Due to these severe risks, youll need strict medical supervision to manage potential complications

10.1038/s41413-018-0016-9 104 GwonM.-G.AnH.-J.GuH.KimY.-A.HanS

By targeting the brains hunger and satiety centers, this treatment can lead to: This therapy may be right for: Note: This therapy is not for individuals with a history of medullary thyroid cancer, pancreatitis, or specific endocrine disorders

DOI: 10.1186/1471-2431-11-111

For researchers who experience significant gastrointestinal side effects , an 8mg maintenance dose delivers nearly equivalent results with better tolerability