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The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo

Phosphopeptides were eluted in three rounds with 80 l 1% ammonia for 20 min, transfered the supernatant to a clean plate, and acidified with TFA

This impaired clearance would also be compounded by exogenous copper downregulating LRP1 expression (Singh et al., 2013), that could further impede CNS clearance of LRP1 ligands such as Tau or A

The data discussed here summarize some of the roles of endogenous estrogens, estrogen-based therapies, and estrogen-like molecules on brain homeostasis, particularly in neurogenesis, gliogenesis, and regulation of the neuroprotection/neurodegeneration balance

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