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Since the majority of paracetamol absorption in the gastrointestinal tract occurs within the first 4 h[40], activated charcoal is generally believed to be most beneficial if administered within that time period, as its mechanism of action is to interfere with paracetamol absorption

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Through machine learning methods, three key genes (SRPK1, BIRC2, and KLHL3) were identified, and their significance was validated in other datasets and clinical patients (Huang et al., 2023)

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IGFBP-4 is present in various brain regions and is critical in neural stem cell differentiation, cerebellar plasticity, and astrocytic microtubule function [114]

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