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272 , G1355G1364 (1997)

Fact: High doses mean very little if the body cannot absorb them

Collectively, these findings suggest that ROS-induced OS plays a pivotal role in steatosis, inflammation, and apoptosis, contributing significantly to the progression of ALD

Furthermore, celastrol exhibited its capacity to improve cardiac function by suppressing the activation of NLRP3 inflammasomes and decreasing the expression of ASC, cleaved IL-1, and cleaved IL-18