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By moderately promoting oxidative stress, the antioxidant defense mechanisms of vascular endothelial cells can be activated, reducing the formation of oxidized LDL and thus alleviating the progression of atherosclerosis [197]

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Recent studies have suggested that IF inhibits the nuclear factor kappa-B signaling pathway, which is an important regulator of downstream parameters including TNF- and IL-6 (25), which is consistent with the results that IF could partly eliminate the inflammation caused by adipose tissue, with lower CRP and TNF- (26)

This includes adhesion to hyaluronan and other components of the extracellular matrix, as well as axon deterrence and action as a scaffold for enzymes and growth factors

At the same time, the right rules were being followed