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Smad3 is an important mediator of renal fibrosis (Meng et al., 2013)

CRISPR/Cas9-mediated targeting of ABCC1 in THP-1 cells significantly increased intracellular Venetoclax levels as compared to THP-1 AAVS1.1 control cells (Fig

Ghimire S, Kyung E, Lee JH, Kim JW, Kang W, Kim E (2013) An evidence-based approach for providing cautionary recommendations to sulfonamide-allergic patients and determining cross-reactivity among sulfonamide-containing medications

For example, when pregnant mice were exposed to ZnO nanoparticles, ZnO nanoparticles could pass through the blood-brain barrier, and reach the fetal brain, causing microglial inflammation and eventually leading to nervous system damage in fetal mice