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Aging, diabetes, obesity, liver disease, chronic infections, pollution exposure, alcohol intake, and long-term medication use accelerate this depletion

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Continued monitoring and additional studies are essential to fully understand the long-term safety and efficacy of this therapy ( In this review, we provide an up-to-date understanding of the molecular mechanisms and regulatory pathways involved in A1AT immunomodulatory actions, as well as its homeostatic functions in metal and lipid metabolism

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[1] Cell Line:Senescent Leydig cells Concentration:25 mM Incubation Time:3 days Result:Reduced the viability of senescent as compared to normal TM3 Leydig cells