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There are older human and clinical-observational data involving pineal peptides that suggest possible improvements in mortality, cardiovascular aging, circadian function, and general geroprotection, but those findings are not the same as definitive proof that Epitalon lengthens human life through telomere extension

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These peripheral approaches, when combined with molecular, imaging, and behavioral measures, underscore the need to evaluate biomarkers not in isolation but as part of an integrative framework, setting the stage for broader implications in both research and clinical practice

A decrease in SHBG levels leads to an increased level of free testosterone in the blood and promotion of androgenic activity

J Pharmacol Exp Ther 1994