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Methods General procedure for synthesis of 11-boronate ester MG-EG (4a) Starting material MG-EG ( 4 ) (50 mg, 0.11 mmol), [Ir(COD)OMe] 2 (3.6 mg, 5.5 mol, 5 mol%), 3,4,7,8-tetramethyl-1,10-phenanthroline (3.9 mg, 16 mol, 15 mol%) and B 2 Pin 2 (111 mg, 0.44 mmol, 4 equiv.) were balanced into an oven dried vial

Unlike synthetic HGH, injection frequencies can be decreased or stopped altogether once optimal levels are sustained with sermorelin

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Function: It increases GH and insulin-like growth factor 1 (IGF-1) production without raising prolactin levels significantly

Sierra-Johnson J, Romero-Corral A, Somers VK, Lopez-Jimenez F, Mlarstig A, Brismar K, Hamsten A, Fisher RM, Hellnius M-L

Availability of MRI was encouraged, but not obligatory