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Crucially, these findings stem primarily from small, heterogeneous studies using non-standardized extracts/doses, lack robust evidence, and focus on biochemical or symptomatic surrogates rather than clinically relevant hard endpoints, such as endoscopic remission, reduced hospitalizations, or avoidance of surgery

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GABA serves as a non-toxic osmolyte, effectively mitigating ROS and thereby augmenting stress tolerance in plants (Carillo 2018)

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Vildagliptin improves high glucose-induced endothelial mitochondrial dysfunction via inhibiting mitochondrial fission