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[9] These proteins are members of the family of ATP-binding cassette transporters and can catalyse the ATP-dependent transport of a huge variety of hydrophobic anions, [10] and thus act to remove phase II products to the extracellular medium, where they may be further metabolised or excreted

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References Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al

By decreasing demand for ATP by suppressing ATP consuming processes, cells lower their rate of O 2 consumption and delay the development of anoxia which, unlike hypoxia, can cause cell death

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