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To produce thyroid hormones, the gland actually creates a small amount of oxidative stress as a byproduct

2021;158 doi: 10.1016/j.nbd.2021.105467

The major limitations of these studies included were small sample size consisting of healthy Volunteers, extremely short study periods with an even shorter follow- up and Lack of measurement of Blood Levels of Glutathione.The investigators also did not estimate baseline or post- treatment renal or thyroid function of the Subjects, both of which were reported to be adversely affected by IV glutathione

There was significantly less lipid peroxidation in ALA treated retina (*p = 0.006) (n = 8 per group)

Furthermore, excitotoxic damage has been shown to significantly elevate HO-1 protein expression in primary astrocyte cultures, accompanied by translocation of the protein to the nucleus (Li et al., 2004)

The induction of hyperthyroidism in rats is associated with oxidative stress in the testes as reflected by increased lipid peroxidation, elevated GSH levels and induction of antioxidant enzymes