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Research showed that cellular damage, such as ferroptosis and pyroptosis, might intensify the process of tau hyperphosphorylation and an inflammatory response linked to AD progression (Qiu et al., 3 Mechanisms of ferroptosis Ferroptosis is characterized by unchecked peroxidation of lipids and consequent disruption to the cellular membrane, its onset and development are controlled by intricate signaling and regulatory mechanisms

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In this review, we outline the pathogenesis of ferroptosis, regulatory mechanisms of ferroptosis, related regulatory molecules, and their effects on epilepsy, providing a new direction for discovering new therapeutic targets in epilepsy

Biochem Pharmacol 63 : 14231430