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Studies indicate that diminished VEGF expression precipitates neurodegeneration by compromising neural tissue perfusion, thus exacerbating neuronal vulnerability to ischemic insults and metabolic imbalances (Oosthuyse et al

H 2 O 2 -induced cell death was also reproduced in primary neurons and was found to be attenuated by extracellular Ca 2+ removal with abolishing TRPM2 activation

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N Engl J Med 1990;322:223-8.ArticlePubMed 59

Powerful antioxidant: Glutathione is one of the body's most important natural antioxidants