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In the SEARCH for Diabetes in Youth (SEARCH) study, youth with T2D were found to have significantly higher urinary albumin-to-creatinine ratios than youth with T1D (126), and this difference remained significant after multivariable adjustment for obesity, hypertension, and dyslipidemia, all known risk factors for DKD that are more prevalent in youth with T2D vs

Proc Natl Acad Sci 103:81558160

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Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of acetyl-L-carnitine, n-3 fatty acids, and coenzyme Q10

Lactylation, a post-translational modification (PTM) identified in 2019, introduces a novel mechanism by which lactate can modulate protein function and gene expression [3]