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10.1155/2021/9278441 101 ShiZ.YaoF.ChenQ.ChenY.ZhangJ.GuoJ.et al (2024)

Mechanistically, AUR disrupts redox-homeostasis by irreversibly binding to the selenocysteine active site of intracellular TrxR, thereby inhibiting Trx reduction and impairing ROS detoxification [38]