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However, if the condition persists, the development of nonfat breast tissue around the nipple area requires surgery to remove or will otherwise be permanent

Additionally, it is known that markers of OS in the brain, such as lipoperoxidation, are higher in male brains than female brains 21,22

This is counterbalanced some times by the tendency of many to consume less animal products and therefore to include more carbohydrates

For instance, amifostine exhibits remarkable individual differences in efficacy and toxicity: it requires alkaline phosphatase (ALP) for conversion in vivo to exert its effects, and varying ALP levels among tumor patients affect the production of its active metabolites, thereby influencing therapeutic efficacy (192)

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