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Therefore, to monitor the structural variations and quality of each docked receptor-ligand complex, RMSD and RMSF values for the ()alpha-carbon atoms of the protein were calculated in reference to the first pose of the MD simulation and analyzed by comparison to the respective values of the -carbon atoms in the apo-mh-Tyr structure (Figs

The uric acid was dissolved in the cell-growing medium without any supplements to reach the following concentrations: 200 M, 400 M, 500 M, 800 M, and 1000 M

Mutation of a critical arginine in microsomal prostaglandin E synthase-1 shifts the isomerase activity to a reductase activity that converts prostaglandin H2 into prostaglandin F2alpha

Ubiquitin facilitates a quality-control pathway that removes damaged chloroplasts

SlTOE1B antagonises GCR1/2 in gland formation To elucidate the mechanism that by which GCR1/2 inhibits gland formation, we performed a yeast two-hybrid screen for GCR1 interactors in a yeast cDNA library that was constructed with tomato trichomes and shoot apical tissues

RESULTS A total of 29516 participants were included in the analysis for hyperuricemia (study population A)