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So far, HRMS-based methods for HBM of mycotoxins have been used only sporadically but the call for comprehensive multi-analyte methods seems to promote their use in this field (Debegnach et al

But also work together in what known as antioxidant cycling

Data were processed with the XDS program package 28

Nrf2 (NF-E2-related factor 2), a transcription factor in humans that is encoded by the NFE2L2 gene, regulates the expression of a set of antioxidant and detoxifying genes, protecting the body from the ravages of oxidative stress-related conditions, including (but not limited to) those affecting the brain and nervous system

10.1038/nrd3403 [DOI] [PMC free article] [PubMed] [Google Scholar] Finkel T

This review underscores the critical role of ageing in PD development and explores how age-related neuronal decline contributes to substantia nigra loss and PD manifestation in susceptible individuals