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aeruginosa , and Burkholderia fungorum , the oxidation of formaldehyde to formate occurs in a single step that is independent of thiol, pterin, or RuMP (Marx et al., 2004

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The triple amino acid mutation at M252Y/S254T/T256E (the YTE modification) was shown to promote a fourfold increase in serum half-life of mAbs due to increased binding to FcRn 84 , and was used in tixagevimab and cilgavimab on top of the TM modification (see above) to extend their half-life 76

We used 500 ng of total RNA isolated from WT and KO cells at PFG stage and day 8 of spontaneous differentiation, treated with H 2 O 2 , to prepare libraries (TruSeq RNA Library Prep Kit v2) according to the manufacturers protocol

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To combat this, the use of induced pluripotent cells from the affected individuals to deduce the metabolic fate of compounds could also be seen as a potential option in future