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Among the proposed mechanisms for these effects, the reduction of toxic metabolites from fatty acids, especially LCAC under ischemic conditions, increased glucose oxidation during reperfusion, and consequently the reduction of lactate and H+ ion accumulation, resulting in the inhibition of acidosis in myocardial cells during ischemia, as well as the inhibition of harmful effects of free radicals released during reperfusion, are more prominently noted

For instance, in Huxu yellow-feathered chickens, an indigenous Chinese breed, the diameter and cross-sectional area of breast myofibers were observed to decrease linearly, and the myofiber density was increased with increasing ME intake during the finisher phase

Activation of fatty acids to highly polar thiol esters, i.e., acyl-CoA, occurs on the outer mitochondrial membrane, but to enable transport across the inner mitochondrial membrane, the acyl group is transferred to carnitine with formation of acylcarnitines, which can enter the mitochondria with the assistance of translocases

Nutrients 9:387

As an aldehyde intermediate, it requires careful handling by the cell to prevent potential toxicity

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