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the peptide or protein may be unmodified or may be modified, e.g., at its N-terminus, at its C-terminus and/or at a functional group in the side chain of any of its amino acid residues (particularly at the side chain functional group of one or more Lys, His, Ser, Thr, Tyr, Cys, Asp, Glu, and/or Arg residues)

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Kessova, I

Animal experiments After a 1-week acclimatization period, male C57BL/6 mice were orally gavaged with 150 mg/kg of metformin

doi: 10.3389/fimmu.2019.00423 54 MuraoAAzizMWangHBrennerMWangP

Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice