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10.1109/tbme.2024.3517635 15

[DOI] [PMC free article] [PubMed] [Google Scholar] 132.Li Y., Xu S., Mihaylova M.M., Zheng B., Hou X., Jiang B., Park O., Luo Z., Lefai E., Shyy J.Y.-J., et al

Concurrently, this intervention has been shown to reduce the prevalence of pathogenic bacteria, thereby restoring a balanced and homeostatic state within the murine gut microbiota (Niu et al., 2023)

I think when you look at the fact that depression is so strongly correlated to altitude, I think thats a big signal and just the role of serotonin in handling hypoxia

However, there are many topical and systemic treatment options available to reduce symptoms