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Defective intrinsic factor synthesis arises from mutations in the GIF (gastric intrinsic factor) gene and usually presents during infancy, after vitamin B12 stores are depleted (35)

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Scientists isolated a portion of a larger protective protein in stomach secretions and synthesized a stable version for research purposes

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This review discusses the stromal/cancer cell relationship, by using examples to illustrate a number of different ways in which cancer cells can rely on and contribute to their microenvironment both as a stable network and in response to therapy