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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Jong C.J., Sandal P., Schaffer S.W

Furthermore, they observed a strong negative correlation between TRAP values and high plasma ascorbic acid levels in CF patients, suggesting that high concentrations of ascorbic acid might exert a pro-oxidant effect in the context of CF, thereby diminishing the overall extracellular antioxidant defense (Langley et al., 1993)

(2) Departamento de Medicina, Universidade Federal da Bahia- UFBA, Salvador, BA, Brasil Diabetology & Metabolic Syndrome 2026: PO240 Introduction: Diabetes mellitus (DM) has a growing global prevalence, posing a significant public health problem

Moreover, MPH has been shown to promote ROS via RAC1and CAMK4 activation, although the evidence regarding whether MPH use indeed induces or reduces oxidative stress is not clear

Vitamin C synthesis, absorption, accumulation, and excretion follow a complex biochemical pathway converting glucose into glucuronic acid, a key metabolite for detoxification and metabolic regulation