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L-NAME and BPC 157 regimens and dose application were adjusted according to our previous studies (reviewed Alternatively, to perceive the effect of the given medication itself (without L-NAME), rats received only BPC 157 (total dose 10 g/kg or 10 ng/kg as retrobulbar application in each eye, 1 g/0.1 ml saline/each eye, or 1 ng/0.1 ml saline/each eye) or only saline via retrobulbar application in each eye (0.1 ml/each eye) (as an additional control sham group) at the corresponding time point

Gentle swirling motion distributes the solution evenly until full dissolution occurs, avoiding foam formation or structural disruption

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BPC-157 may support intestinal barrier repair by strengthening tight junctions and stimulating epithelial cell regeneration, which seals gaps in the gut lining and prevents unwanted substances from passing into the bloodstream

Regarding plasma B12 - this is not the case, serum B12 often remains highly elevated (well over the normal range) even while symptoms return - this is why testing B12 once treatment begins is not recommended