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This limitation hinders the investigation of the MGBA mechanism in cerebrovascular diseases (239, 240)

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Miao, Y

Deconvolution of these two peaks revealed both native and monoglutathionylated M pro as expected and contained an estimated 35% monoglutathionylated M pro and less than 5% diglutathionylated M pro , with the remaining M pro unmodified (Figure 4B)

61 , 15281532 (2009) Acknowledgements The study was supported by the National Institutes of Health (NIH), the National Institute of Neurological Disorders and Stroke (NINDS), and the Center for Neuroscience and Regenerative Medicine (CNRM) at the Uniformed Services University of the Health Sciencesa collaborative effort between the NIH, the Department of Defense and the Walter Reed National Military Medical Center to develop innovative approaches for brain injury diagnosis and recovery

Studies with a specific inhibitor of ACS, Triacsin c, further revealed that ACS inhibition induces selective apoptosis in cancer cells through the mitochondria-mediated pathway (Mashima et al, 2005)