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Funding The author(s) declare that financial support was received for the research and/or publication of this article

Salidroside improves cognitive function in Parkinson's disease via Braf-mediated mitogen-activated protein kinase signaling pathway

This proteinopathy influences the brain by blocking the generation of substances needed for diverse brain activities, such as thinking, coordination of motion, behavior, and mood [7]

4.2 Formulation technologies and research advances: current dosage forms and doses 4.2.1 Dosage forms Advanced formulation techniques such as nanoemulsion (107), microemulsion (108), liposomes (109), and microencapsulation (110) have been widely applied to enhance the bioavailability and bloodbrain barrier permeability of TCM-derived polysaccharides, saponins, triterpenes, polyphenols, and carotenoids (111, 112)

2 Methodology This review was conducted through a literature search in PubMed, Scopus, Web of Science and Google Scholar, using combinations of keywords such as Parkinsons disease, -synuclein aggregation, sirtuins, insulin signaling, GLP-1 and incretin mimetics phytomolecules, neuroprotection, and therapeutics. The search covered publications from 2010 to January 2026