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Following physical activity, there is a significant reduction of 613% in pro-inflammatory cytokines such as IL- 6, IL- 8, and TNF-, while there is a notable increase of 55% in anti-inflammatory markers like IL- 10

However, long-term therapy (beyond 612 months) should always involve routine lab checks and off periods to avoid overstimulation or diminishing returns

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Environ Toxicol Pharmacol 46:277285 Shaik N, Shanbhog R, Nandlal B, Tippeswamy HM (2019) Fluoride and thyroid function in children resident of naturally fluoridated areas consuming different levels of fluoride in drinking water: an observational study

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