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However, these sites are enriched for CpG (99.3%) islands and almost half of the probes on the array cover intergenic regions, such as bioinformatically predicted enhancers, DNase I hypersensitive sites and validated differentially methylated regions (DMRs).60 61 However, the HM450 platform may miss important regulatory regions

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Therefore, comprehensive and long-term toxicological assessments are warranted to better understand their safety and guide regulatory frameworks (Balusamy et al., 2023

Int J Adv Biol Biomed Res 9:214227 Oda SS, El-Ashmawy IM (2012) Protective effect of silymarin on mercury-induced acute nephro-hepatotoxicity in rats., 9(4)

Mild soreness at the site for a day or two afterwards is normal and feels similar to the morning after a tetanus or flu jab

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