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2011 Oct;41(9):248-53

In addition, IL-1 can strongly upregulates the expression of vascular endothelial cell adhesion molecules and promotes the production of other chemokines, thereby amplifying the recruitment and infiltration of neutrophils and establishing a positive feedback cycle of inflammation (108)

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In the chimpanzee lineage, we argue that an additional sequence exchange between SD1 and SD2 happened before the deletion event