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How often should doses be adjusted

WT) or 50 mg/kg tamoxifen for 5 days (KO)

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Tramiprosate did not show a significant effect in ApoE 3/3 organoids while it led to a downregulation of carnitines (CAR), lysophosphatidylcholines (LPC-O) and oxidized phosphatidylethanols (PE-O), as well as an upregulation of ceramide (CER) in ApoE 4/4 (Fig