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Alzheimers Disease (AD) has been characterized for decades by the presence of histopathological alterations (extracellular amyloid- containing plaques and intracellular tangles of hyperphosphorylated tau-protein) leading to neurodegeneration (synaptic deficits and finally neuronal loss), as well as by severe cognitive deficits

Activation of pyruvate dehydrogenase activity by dichloroacetate improves survival and neurologic outcomes after cardiac arrest in rats

A systematic review also concluded that TB promoted the onset and progression of diabetes (156)

GLP-1 RAs link to gallbladder/biliary diseases without increasing pancreatitis risk

5 Shimizu H, Kiyohara Y, Kato I, Kitazono T, Tanizaki Y, Kubo M, Ueno H, Ibayashi S, Fujishima M, Iida M

doi: 10.1038/nature02282 103 KdkovA.SynytsyaV.KrusekJ.ZmovL.VlachovV