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The safety data comes from extensive cell studies and animal experimentsnot human trials

Interestingly, the bacterium Bacillus oleronius, isolated from Demodex mites infesting the HFs of rosacea patients, has been shown to stimulate an inflammatory response in the skin, thus contributing to disease flares

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doi: 10.1016/j.coi.2014.06.003 12 LewinsohnDALewinsohnDMScribaTJ

However, assessing the environmental and safety impacts of metal-doped CDs-based nanozymes is also significant