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Notably, when these motifs were deleted, the 7NA-GFP construct became trapped within the ER, as observed in Supplemental Figure 2D

Springer Link Krivic A, et al

reads were trimmed using TrimGalore (48) and aligned to Ensemble hg38 using STAR (49)

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[2] [3] [4] Alcohol may also cause death indirectly by asphyxiation, caused from vomiting

When extracellular Cu 2+ entered the mitochondria, FDX1 reduced Cu 2+ to Cu + , leading to oligomerization of DLAT protein, a decrease in the expression of Fe-S cluster proteins, and an increase in the level of toxic stress protein in the heat shock protein family A (HSP70), thereby inducing protein toxicity stress and cell death [6]