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While SCLC is mostly chemosensitive in frontline therapy, the inevitable disease relapse in most patients and the subsequent chemoresistance remain formidable problems leading to very poor overall outcome (Ma and Salgia, 2004)

PTD-DBM is more narrowly targeted, focused specifically on removing CXXC5 suppression of Wnt signaling

The nanocomposite exhibited anti-AD efficacy by targeting hyperphosphorylated Tau, facilitating the monitoring of Tau retention using MRI/PET, reducing oxidative stress, and preventing hyperphosphorylated Tau aggregation, so providing effective Tau-targeted theranostics [42]

Oral supplements are available, but they must pass through the GI system and absorption may vary

These reflect the core features of anxiety disorders,including intense worry, panic attacks, and physical manifestations such as hypervigilance and fear responses 47

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